Chromatography

Dr. Norberto Guzman received a B.Sc. degree in biochemistry from the University of Chile, Santiago, Chile; a M.Sc. degree in biochemistry (cell and molecular biology) from the Medical College of Georgia, Augusta, Georgia, U.S.A.; and a Ph.D. degree in biochemistry from a Joint Graduate Program of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School and Rutgers, The State University of New Jersey, New Brunswick, New Jersey, U.S.A. Dr. Guzman has worked for the last 30 years in academic medical institutions, diagnostic and pharmaceutical companies, including Mount Sinai School of Medicine, Roche Diagnostic Systems, Hoffman-La Roche, and Johnson & Johnson. He is currently the Chief Scientific Officer-Director of Research at Princeton Biochemicals, Inc. Princeton, New Jersey, U.S.A.

Dr. Norberto Guzman main research interest is in the studies of protein biomarkers in biological fluids using miniaturized immunoaffinity capillary electrophoresis instruments.

Gilles Goetz is a Principal Scientist at Pfizer in Groton, Connecticut, USA. Gilles received his B.Sc. (1991) and Ph.D. (1995) at the University of Strasbourg in France. After post docs at the University of Hawaii (1996-97) and of Neuchatel (CH) (1998-99) studying marine and fungal natural products, he joined Monsanto in 2000. There he worked through mergers and acquisitions for Pharmacia and Pfizer successively in the Natural Product group, the HTS group (analytical support), and the Purification Group. In 2010 he transferred to the Expert Purification Group at Pfizer Groton and in 2011 to the Molecular Properties Group. He is part of the team influencing medicinal chemistry design through insights into molecular properties such as polarity, lipophilicity, shape, and conformation that will impact molecular behaviors like solubility, permeability, and efflux. They develop and use mainly chromatographic techniques (EPSA) to assess those properties, and work towards predicting molecular behaviors.

SFC, HPLC applications, Immobilized Artificial Membrane (IAM) chromatography as well as Micellar Liquid Chromatography (MLC), along with EPSA

Prof. Ravi Bhushan has an expertise in enantiomeric resolution of compounds of pharmaceutical importance using liquid chromatography. So far, he has guided 28 doctoral and 50 Masters’ theses, published more than 230 research papers in international refereed journals and chapters in books and encyclopedia. He edited four Special Issues of Biomedical Chromatography on Chiral Resolutions as Guest Editor. He received Alexander von Humboldt fellowship of Germany in 1988, and European Economic Community Fellowship in 1992. He is an elected Fellow of the Royal Society of Chemistry, London, and Fellow National Academy of Sciences India, (FNASc). He received the ‘Outstanding Teacher Award’ of the year 2007 of IIT Roorkee, and Khosla Research Prize and Silver Medal of Univ of Roorkee.

Ravi Bhushan current interest includes enantioseparation with both achiral phases of chromatography in the absence of any external chiral species.